site stats

Ttc9a

WebAbstract. Tetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone.It is over-expressed in breast cancer. However, little is known about the physiological function of TTC9A.The objectives of this study were to establish a Ttc9a knockout mouse model and to study the consequence of Ttc9a gene inactivation. The … WebUniProtKB unreviewed (TrEMBL) Organism. Catharus fuscescens (Veery) Amino acids. 181. Protein existence. Predicted. Annotation score. 1/5.

Smeeta Shrestha - Research Fellow - LinkedIn

Web15 rows · Mar 21, 2024 · GeneCards Summary for TTC9 Gene. TTC9 (Tetratricopeptide Repeat Domain 9) is a Protein Coding gene. Diseases associated with TTC9 include Large … WebSep 6, 2024 · It is plausible therefore that TTC9A negatively regulates ERalpha activity through interacting with co-chaperone proteins such as FKBP38 and FKBP51. TTC9A acts … greenleaf greenhouse snydertown pa https://mellowfoam.com

TTC9A deficiency induces estradiol-mediated changes in …

WebApr 1, 2024 · We aimed to investigate the interactive roles of TTC9A and estradiol modulation on behavioral neuroplasticity. The tail suspension immobility data and brain … WebSep 6, 2024 · It is plausible therefore that TTC9A negatively regulates ERalpha activity through interacting with co-chaperone proteins such as FKBP38 and FKBP51. TTC9A acts as a chaperone protein to facilitate the function of tropomyosins (including Tm5NM-1) in stabilizing microfilament and it may play a role in cancer cell invasion and metastasis WebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and estradiol activity is negatively regulated by TTC9A, we hypothesized that the behavioral changes induced by Ttc9a-/- is also mediated by neuroplasticity-related mechanisms. fly from oakland to los angeles

Tetratricopeptide repeat domain 9A is an interacting …

Category:TTC9A deficiency induces estradiol-mediated changes in

Tags:Ttc9a

Ttc9a

Truncation constructs of TTC9A protein and their ... - ResearchGate

WebTetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone. It is over-expressed in breast cancer. However, little is known about the physiological … WebDC Field Value Language; dc.contributor.author: Lim, Lee Wei: en: dc.contributor.author: Shrestha, Smeeta: en: dc.contributor.author: Or, Yu Zuan: en: dc.contributor ...

Ttc9a

Did you know?

WebNumber of male and female pups from Ttc9A KO mice crosses. There is no 13 significant difference in the male and female offspring ratios from Ttc9a+/+ X Ttc9a+/+, 14 Ttc9a+/-X Ttc9a+/-and Ttc9a-/-X Ttc9a-/- crosses. 15 16 (Table S3) Supplementary Table 3. Organ Weights of female Ttc9a KO mice at 3 weeks 17 and 6 weeks of age 18 Webstudies in TTC9A knockout (TTC9A−/−) mice have indicated that TTC9A negatively regulates the action of estrogen. In this study we investigated the role of TTC9A on …

WebTTC9A deficient mammary gland showed significant increase in mammary ductal elongation and branching on estrogen and progesterone treatment, demonstrating aberration in hormone receptor signaling in absence of TTC9A.These observations suggest that TTC9A negatively regulates mammary gland development and the possibility that … WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system has been reported. Emerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neurop …

WebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the possible mechanisms of TTC9A on estradiol and neuroplasticity-related changes remain obscure. In this study, we investigated the effects of TTC9A and estradiol WebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the …

WebTTC9A to be 222 aa. Using mouse polyclonal antibody generated against TTC9A protein, TTC9A was shown to be ubiquitously expressed in human tissues. In breast cancer cells, TTC9A was predominantly concentrated to the endoplasmic reticulum and was regulated by a number of factors, such as growth factors, serum factors and steroid hormones [2]. green leaf graphic designWebApr 1, 2024 · In brief, Ttc9a-/-and wildtype female mice were subjected to ovariectomy (OVX) as reported (Lim et al., 2016; Lin et al., 2001). After a 10-day recovery period, mice were administered a subcutaneous injection of either 10 μg/kg 17-β-estradiol benzoate . Effects of Ttc9a-/-and estradiol modulation on tail suspension immobility fly from oakland to las vegasWebMay 2009 - Sep 20123 years 5 months. Nanyang Technological University, Singapore. • Perform hands-on wet lab work to generate TTC9A mutant … fly from ny to orlandoWebWe'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2024 ... fly from oklahoma city to san salvadorWebSep 14, 2012 · 1. Introduction. Tetratricopeptide repeat domain 9A (TTC9A) is a member of TTC9 family proteins that also include TTC9B and TTC9C. Human TTC9A gene was first identified by sequence analysis of a cDNA clone from a brain cDNA library .It was confirmed to code for a 222 amino acid TTC9A protein in human using mouse polyclonal antibody … greenleaf grill in little rockWebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and … green leaf grill little rockWebTo understand the effects of TTC9A and estradiol modulation on neuroplasticity functions, we performed a behavioral analysis of tail suspension immobility and neuroplasticity … fly from oahu to lanai