WebFeb 26, 2024 · Cells with CBX4 overexpression were transfected with two HDAC1 siRNAs (siHDAC1 #1 and #2). The binding ratio of CBX4 on KLF6 promoter was determined by ChIP assays. *P<0.05 (Student's t-test). e. The mRNA expression of KLF6 in ACHN and RCC4 cells were examined by qRT-PCR, following the transfection of HDAC1 siRNA for 36 h. *P<0.05 … WebKLF6 - Function 1 GENE 3 ISO 53 REF Gold Only Extend overview KLF6 → Krueppel-like factor 6 Protein also known as : Suppressor of tumorigenicity 12 protein . Gene name : KLF6 Family name : Krueppel C2H2-type zinc-finger protein Entry whose protein (s) existence is based on evidence at protein level. Show evidences
Autologous T cells expressing the oncogenic …
WebNov 22, 2024 · KLF6 function in the regulation of tumor growth has been validated through several approaches. KLF6 expression attenuates the tumorigenicity of glioblastoma … WebFeb 1, 2024 · T cells are central players of the adaptive immune response. They recognize, via their T cell receptor (TCR), a peptide fragment of antigen (Ag) in association with class I or II molecules of the major histocompatibility complex (MHC). bateria para sail 2014
Krüppel-like factor 6–mediated loss of BCAA catabolism ... - PNAS
WebApr 11, 2024 · CD4+CD8+ T-cells and acinar cells have the greatest transcriptional changes post-IR ... KLF6 also inhibits cell proliferation and is co-regulated with KLF2 in MCF-345 7 cells 70. Thus, high levels of KLF2 and KLF6 coupled with a lack of cytokines and chemokines 346 on the DEGs suggest that the increase in CD4+CD8+ T-cells may … Webstantially perturb KLF6 levels, suggesting post-transcriptional regulation of KLF6 in PDAC. Lee et al. demonstrate that OAT inhi-bition results in transcriptional alterations in PDAC cells and provide data, obtained using the sequencing technique ATAC-seq, to suggest an epigenetic basis for these changes. WebKruppel-like factor 6 (KLF6) is a member of the zinc finger family of transcription factors that regulate key cellular processes such as development, differentiation, proliferation, and programmed cell death ( 13. ). Recent studies have linked Kruppel-like factors (KLFs) to the biology of macrophage activation and polarization ( 14. , 15. ). bateria para samsung a02