Cytoprotective activity molecular docking
WebJan 25, 2024 · Quantum mechanical, molecular docking, molecular dynamics, ADMET and antiproliferative activity on Trypanosoma cruzi (Y strain) of chalcone (E)-1- (2 … WebJul 29, 2024 · Interestingly, the cytoprotective activity of compound 12, with the highest antioxidant potential in cell-free assays, is similar to the cytoprotective activity of compounds 4, 5 and 7–8.
Cytoprotective activity molecular docking
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WebMay 12, 2024 · Molecular docking analysis revealed that compound 1 has better docking efficiency and forms hydrophobic interactions with five amino acids (ARG192, … WebThe majority of the 9β-halogenated analogs have a docking score even greater than that of nocloprost, indicating that these compounds could have potential cytoprotective activity. Correlations between docking score and substituents on the prostaglandin skeleton have been done. Keywords: 9β-halogenated prostaglandins; molecular docking ...
WebAug 23, 2024 · It was found that some derivatives of 3-(arylmethylamino)-6-methyl-4-phenylpyridin-2(1H)-ones under the conditions of our experiment had a pronounced … WebAug 1, 2024 · The molecular docking was carried out using the Haddock server (version 2.2) to further characterize the interaction mechanism between peptides and antioxidant …
WebAt the same time C 55 H 40 O 34 increased expression of heme oxygenase-1 and NAD(P)H: quinone oxidoreductase and mitochondrial complex I and V activities. Results from this study demonstrates a potent antiglycation activity of C 55 H 40 O 34 in vitro and indicates its possible therapeutic application in glycation related diseases. WebJan 21, 2024 · One of the existing markers for cancer chemoprevention is the induction of phase II detoxifying enzyme NAD (P)H:quinone oxidoreductase 1 (NQO1), which plays a vital role in cytoprotection against oxidative damage. The extracts were assessed to test their chemopreventive potential via NQO1 enzyme induction.
WebIn general, dose escalation may be possible by cytoprotective agents that prevent cisplatin-related side-effects without interfering with antitumor activity (Alberts and Noel, 1995). …
WebStructure and activity relationships were then studied via 1 H NMR, 13 C NMR, mass spectral and in silico docking analyses, as well as cell viability measurements. We found that the compounds exhibited substantial affinity levels towards ER alpha (ERα). billy serialWebCytoprotective Activity of p-Terphenyl Polyketides and Flavuside B from Marine-Derived Fungi against Oxidative Stress in Neuro-2a Cells YURCHENKO EKATERINA Y. 1 , Menchinskaya Ekaterina S 1 , Pislyagin E.A. 1 , Chingizova Ekaterina A 1 , Girich Elena V 2 , Yurchenko Anton N 2 , Aminin Dmitry L. 1, 3 , Mikhailov Valery V. 4 billy serowWebJan 18, 2024 · In this study, chromone derivatives were evaluated for their inhibitory activity against COX-2. The studied compounds were also docked into the active sites of both … cynthia coates murderWebAug 1, 2024 · Cytoprotective activity Molecular docking Antioxidants Abbreviations ROS Radical Oxygen Species Keap1 Kelch-like ECH-associated protein 1 Keap1-Nrf2 Pathway Keap1/nuclear factor erythroid 2-related factor 2 (Nrf2) pathway CAT Catalase SOD Super Oxide Dismutase GPX Glutathione Peroxidase NF-КB Pathway Nuclear Factor- Kapa B … cynthia cobourn 192WebNov 16, 2006 · The cytoprotective protein C pathway for APC anti-inflammatory activity. Anti-inflammatory effects of APC include APC's effects on vascular endothelial cells and APC's effects on leukocytes. Inhibition of inflammatory gene expression on endothelial cells by APC is EPCR and PAR-1 dependent (green arrow). billy series bookcase sizesbilly services bvWebHindawi cynthia coe