Cst plin2
WebGene target information for PLIN2 - perilipin 2 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. WebMay 15, 2014 · Background Perilipin 2 (Plin2) is a lipid droplet protein that has roles in both lipid and glucose homeostasis. An increase in Plin2 in liver is associated with the development of steatosis, glucose intolerance, and …
Cst plin2
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WebAug 28, 2024 · Lipid droplets (LDs) are lipid storage organelles that consist of a central core of neutral lipids surrounded by a phospholipid monolayer decorated with a unique set of integral and peripheral proteins. Invariably, at least one member of the perilipin family of proteins (PLIN1-5) associates with LDs in all cell types. Despite key roles of PLIN2 in … WebResults The algorithm for NASH using PLIN2 mean florescence intensity (MFI) combined with waist circumference, triglyceride, alanine aminotransferase (ALT) and presence/absence of diabetes as covariates had an accuracy of 93% in the discovery cohort and of 92% in the validation cohort. Sensitivity and specificity were 95% and 90% in the …
WebApr 28, 2024 · Moreover, PLIN2 knockout mice are resistant to diet-induced obesity, fatty liver disease and alcohol-induced steatosis, suggesting that PLIN2 is responsible for lipid accumulation, particularly in the liver [41, 42]. Taken together, these studies suggest that PLIN2 promotes LD formation and thereby protects TG from lipolysis. WebMonoclonal Antibody for studying perilipin. Cited in 227 publications. Validated for WB, IP, IHC, IF, IF. Available in 2 sizes. Highly specific and …
WebMar 29, 2024 · Upregulated monocyte expression of PLIN2 is associated with early arterial injury in children with overweight/obesity. Pisano E, et al. Atherosclerosis, 2024 Jun. PMID 34044206. Correlation of perilipin 2 and lipid metabolism in elective cesarean section and vaginal delivery: a prospective study with oxidative and apoptotic pathways. WebJan 1, 2024 · Abstract. Cholesteryl esters (CEs) are the water-insoluble transport and …
WebJun 16, 2016 · Twenty microgram of protein was analyzed by western blot with antibodies against PLIN2 (Proteintech) and ACTIN (CST). HRP coupled secondary antibodies were obtained from Abcam. Chemiluminescence …
WebSep 13, 2024 · Myelin uptake increases PLIN2 expression in macrophages in a PPARγ-dependent manner. Demyelinating lesions are characterized by the abundant presence of foamy macrophages loaded with cholesterol-containing LDs [].As PLIN2 is the main LD-associated protein on cholesterol-containing LDs and given its key role in LD biology [], … how do you become a high priestessWebPLIN2 knockdown in the RVLM blocked the number of iNOS + and PCNA + microglia, … how do you become a hells angelWebMar 21, 2024 · PLIN2 (Perilipin 2) is a Protein Coding gene. Diseases associated with PLIN2 include Sebaceous Adenocarcinoma and Chanarin-Dorfman Syndrome . Among its related pathways are Selective … how do you become a helicopter pilotWebMar 15, 2024 · Background: PLIN2 (adipose differentiation-related protein) belongs to the … pho fakeWebAug 1, 2012 · The plin2-EYFP or plin1ΔC-EYFP fragment was shuttled into the transformation vector pUAST-attB through EcoRI and XbaI sites. All constructs requiring PCR amplification were confirmed by sequencing. All quantitative RT-PCRs were performed on an ABI PRISM 7900HT real-time cycler (Applied Biosystems) using Power SYBR … pho express panama city beachWebSep 26, 2024 · The role of perilipin 2 in Pseudomonas aeruginosa pulmonary infection. Rab18 binds PLIN2 and ACSL3 to mediate lipid droplet dynamics. Lipid droplets are both highly oxidized and Plin2-covered in hepatocytes of diet-induced obese mice. Perilipin2 inhibits diabetic nephropathy-induced podocyte apoptosis by activating the PPARgamma … pho ewa beachWebMay 15, 2014 · Perilipin 2 (Plin2) is a lipid droplet protein that has roles in both lipid and glucose homeostasis. An increase in Plin2 in liver is associated with the development of steatosis, glucose intolerance, and … how do you become a headteacher